Calan 40mg 50 Tablets

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Medicine

Detail Description

Calan Tablets 40Mg (1 Bottle = 50 Tablets) Specification

Requires Prescription:
Yes

Generics

Verapamil Hydrochloride

Used For

  • Hypertension

  • May also be useful in certain arrhythmias and angina (as per physician guidance)

How it works

Verapamil belongs to the calcium-channel blocker class.

  • Relaxes blood vessels, lowering resistance and easing the workload of the heart.

  • Increases oxygen and blood supply to the heart muscle.

  • Slows electrical conduction through the heart to help control heart rate.

Usage and Safety

Dosage:
As prescribed by a physician (contains Verapamil Hydrochloride).

Side Effects

  • Common: Constipation, dizziness, nausea, headache, fatigue, edema, flushing.

  • Cardiac: Bradycardia, AV block, angina pectoris, atrioventricular dissociation, palpitations, syncope, CHF (congestive heart failure), myocardial infarction (rare).

  • Other: Dyspnea, rash, chest pain, claudication, purpura (vasculitis), diarrhea, dry mouth, gastrointestinal upset, gingival hyperplasia, blurred vision, tinnitus, increased liver enzymes.

Drug Interactions

  • HMG-CoA reductase inhibitors (statins)

  • Ivabradine

  • Beta-blockers

  • Digitalis

  • Disopyramide

  • Flecainide

  • Quinidine

  • Alcohol

  • Nitrates

  • Cimetidine

  • Lithium

  • Carbamazepine

  • Rifampin

  • Phenobarbital

  • Cyclosporin

  • Theophylline

  • Telithromycin

  • Clonidine

Indication

  • Treatment of hypertension

  • May also be used (with physician guidance) in management of angina and certain cardiac arrhythmias

When not to Use (Contraindications)

Do not use in patients with:

  1. Severe left ventricular dysfunction

  2. Hypotension (SBP < 90 mmHg) or cardiogenic shock

  3. Sick sinus syndrome (unless patient has a functioning pacemaker)

Precautions

  • Verapamil is extensively metabolized in the liver → use cautiously in patients with impaired hepatic function.

Warnings

  1. May cause a drop in blood pressure below normal → dizziness or symptomatic hypotension may occur.

  2. Has a negative inotropic effect (weakening of heart contraction), but usually balanced by reduced vascular resistance.

  3. Elevated liver enzymes (transaminases, alkaline phosphatase, bilirubin) have been reported in some patients.

Pregnancy Category

Always consult a physician before use.

Storage

Yes – Store at room temperature, away from direct light and heat.