Avsar 14 Tablets x 160 / 10mg

Avsar Tablets 160/10 mg
(1 Box = 2 Strips | 1 Strip = 7 Tablets)

Requires Prescription: Yes

Generics:
Amlodipine Besilate + Valsartan

Used For:
Hypertension

How it Works:
Amlodipine and Valsartan are antihypertensive agents with complementary mechanisms. Together, they provide an additive effect in lowering blood pressure more effectively than either drug alone.

Usage & Safety

Dosage:
As prescribed by the physician.

Side Effects:

• Common: Nasopharyngitis, influenza, hypokalemia, headache, fatigue, edema (facial, peripheral, pitting), flushing, anorexia, hyperlipidemia, hyperuricemia, dizziness, visual impairment, palpitations, cough, abdominal discomfort, constipation, diarrhea, nausea, rash, arthralgia, back pain.

• Rare but Serious: Orthostatic hypotension, tachycardia, coordination abnormalities, hyponatremia.

Drug Interactions:

• Antihypertensives

• Grapefruit & grapefruit juice

• CYP3A4 inhibitors (e.g., azole antifungals, macrolides, verapamil, diltiazem)

• CYP3A4 inducers (e.g., rifampicin, Hypericum perforatum)

• Simvastatin, Lithium

• Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium

• NSAIDs

• Sildenafil

Indication:

Treatment of essential hypertension.

When Not to Use:

• Hypersensitivity to Amlodipine, Valsartan, dihydropyridine derivatives, or any excipient.

• Severe hepatic impairment, biliary cirrhosis, cholestasis.

Precautions:

• Use cautiously in patients with unilateral/bilateral renal artery stenosis or solitary kidney (monitor urea & creatinine).

Warnings:

1. Concomitant use with potassium-raising agents requires caution and potassium monitoring.

2. Safety in hypertensive crisis not established.

3. Discontinue immediately if angioedema occurs; do not re-administer.

Pregnancy Category: Consult physician before use.

Storage: Store at room temperature, away from direct light and heat.