Augmentin 375mg 6 Tablets

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Medicine

Detail Description

Augmentin Tablet 375 mg (1 Strip = 6 Tablets) Specification

Requires Prescription: Yes

Generics:
Amoxicillin, Clavulanic Acid

Used For:
Bacterial Infection

How it works:
The beta-lactamase inhibitory action of clavulanate extends the spectrum of amoxicillin to cover a wider range of organisms, including many resistant to other beta-lactam antibiotics.


Usage and Safety

Dosage:
As prescribed — contains Amoxicillin and Clavulanic Acid.

Side Effects:

  • Common: Diarrhoea, nausea, vomiting, indigestion

  • Less common but possible: Mucocutaneous candidiasis, reversible leucopenia (including neutropenia) and thrombocytopenia, dizziness, headache

  • Serious allergic reactions: Angioneurotic oedema, anaphylaxis, serum sickness-like syndrome, hypersensitivity vasculitis

Drug Interactions:

  • Mycophenolate mofetil

  • Probenecid

  • Oral contraceptives

  • Acenocoumarol or warfarin


Indication:
Broad-spectrum antibiotic for the treatment of infections caused by susceptible bacterial pathogens.

When not to Use:
Contraindicated in patients with a history of hypersensitivity to beta-lactams (penicillins, cephalosporins).


Precautions & Warnings

Precaution:
Before initiating therapy, assess history of hypersensitivity reactions to penicillins, cephalosporins, or other allergens.

Warning 1:
Serious and sometimes fatal hypersensitivity reactions (including anaphylactoid and severe skin reactions) can occur, especially in patients with a history of penicillin allergy.

Warning 2:
Prolonged use may cause overgrowth of non-susceptible organisms.

Warning 3:
Adjust dose in patients with renal impairment as per recommendations.


Pregnancy Category:
Consult a physician before use.

Storage:
Store at room temperature, away from direct light and heat.