Anplag 90mg 20 Tablets

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Medicine

Detail Description

Anplag Tablets Specification

Requires Prescription: Yes

Generic Name

  • Ticagrelor

Used For

  • Blood clots

  • Cardiovascular death reduction

  • Myocardial infarction (MI)

  • Stroke prevention in patients with ACS or prior MI

  • Stent thrombosis prevention post-ACS treatment

How it Works

Ticagrelor reversibly interacts with the platelet P2Y12 ADP receptor, preventing signal transduction and platelet activation. Its active metabolite has a similar potency.

Dosage

  • Ticagrelor (standard dosage as prescribed by a physician)

Side Effects

  • Very Common: Bleeding, hyperuricemia, dyspnea

  • Common: Dizziness, syncope, headache, gout, vertigo, hypotension, respiratory bleeding

  • Uncommon: Tumor bleeding, hypersensitivity (including angioedema), intracranial hemorrhage, eye/ear hemorrhage, confusion

Drug Interactions

Avoid with:

  • Strong CYP3A inhibitors: ketoconazole, clarithromycin, ritonavir, etc.

  • Strong CYP3A inducers: rifampin, phenytoin, phenobarbital

  • Aspirin doses >100 mg

  • Simvastatin/Lovastatin >40 mg

  • Monitor Digoxin levels when co-administered

Contraindications

  • History of intracranial hemorrhage

  • Active bleeding (e.g., peptic ulcer)

  • Hypersensitivity to ticagrelor or ingredients

  • Severe hepatic impairment

Precautions

  • Increases risk of bleeding

  • Avoid abrupt discontinuation unless essential

  • Use cautiously in patients with liver disease

Warnings

  1. Dyspnea is a known side effect; usually mild and transient.

  2. Discontinuation risk: Sudden stopping may increase the chance of MI, stroke, or death.

  3. Hepatic impairment: Use with caution; limited data available.

Pregnancy

  • Consult your physician before use.

Storage

  • Store at room temperature

  • Protect from heat and direct light