Aminovel 600 Infusion 5 % 500ml

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Detail Description

Aminovel 600 – Clinical Nutrition Specification

Requires Prescription:
Yes

Generic Name:

Amino Acid Infusion with D-Sorbitol and Electrolytes

Dosage Form:
Intravenous Infusion Solution (500 mL bottle)

Drug Class:
Parenteral Nutrition / Amino Acid Solution

Description:

Aminovel 600 provides amino acids and energy intravenously to patients who cannot consume adequate nutrition orally or enterally. It is a 5% amino acid solution with sorbitol, electrolytes, and vitamins, formulated for catabolic or protein-deficient states.

Composition (per 1000 mL):

Component Amount
D-Sorbitol 100.0 g
L-Alanine 6.0 g
L-Arginine 6.2 g
L-Histidine 1.0 g
L-Isoleucine 3.2 g
L-Leucine 2.4 g
L-Lysine 2.0 g
L-Methionine 3.0 g
L-Phenylalanine 4.0 g
L-Proline 2.0 g
L-Threonine 2.0 g
L-Tryptophan 1.0 g
L-Valine 3.2 g
Glycine 14.0 g
Ascorbic Acid (Vitamin C) 400.0 mg
Inositol 500.0 mg
Nicotinamide (Vitamin B3) 60.0 mg
Pyridoxine HCl (Vitamin B6) 40.0 mg
Riboflavin Sodium Phosphate 2.5 mg
Electrolytes:  
- Sodium 35 mEq
- Potassium 25 mEq
- Magnesium 5 mEq
- Acetate 35 mEq
- Malate 22 mEq
- Chloride 38 mEq
Water for Injection q.s.

Nutritional Profile:

  • Free Amino Acids: 5% (w/v)

  • Essential Amino Acids (E): 21.8%

  • Non-Essential Amino Acids (N): 28.2%

  • E/N Ratio: 0.7

  • Total Nitrogen: 8.0 g/L

  • Osmolarity: 1320 mOsm/L

Indications:

Recommended for IV nutrition support in patients with:

  • Surgery

  • Severe infections

  • Burns or trauma

  • Gastrointestinal dysfunction

  • Malnutrition

  • Chemotherapy/radiation therapy

  • Prolonged coma

  • Refusal or inability to eat

Dosage & Administration:

  • Maintenance Dose: 0.8–1.0 g protein/kg/day

  • Catabolic States: 1.2–2.0 g/kg/day

  • Usual Adult Dose: 500 mL via IV infusion over 4–6 hours (20–30 drops/min)

  • Adjust Based on: Age, weight, medical condition

  • Use Caution: In elderly or critically ill patients—infuse slowly

Contraindications:

  • Hypersensitivity to ingredients

  • Hereditary fructose intolerance

  • Hepatic coma

  • Azotemia

  • Congestive heart failure

  • Severe acidosis

  • Amino acid metabolism disorders

Precautions:

  • Use cautiously in hepatic/renal impairment, diabetes, and elderly patients

  • High potassium content—monitor in low urine output

  • Use in pregnancy only if benefits outweigh risks

Adverse Events:

Common:

  • Nausea

  • Vomiting

  • Phlebitis

Rare:

  • Hypersensitivity

  • Chest discomfort

  • Palpitations

Packaging:

  • 500 mL plastic bottle

  • Sealed in aluminum foil pouch

  • Includes oxygen absorber to prevent oxidation of amino acids

Storage:

  • Store in a cool, dry place

  • Protect from light and heat

  • Keep out of reach of children

Control Drug:
No

Quick Tips:

  • For intravenous use only

  • Administer under medical supervision

  • Monitor electrolytes, renal/liver function regularly during use