Amclav Ds Suspension 312.5/60ml

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Medicine

Detail Description

Amclav DS Specification

Requires Prescription:
✅ Yes

Generics

  • Amoxicillin

  • Clavulanic Acid

Therapeutic Class:
Penicillin/Beta-lactamase Inhibitor Antibiotic

Used For

Broad-spectrum treatment of bacterial infections, including those caused by beta-lactamase producing bacteria.

How It Works

  • Amoxicillin: A penicillin-class antibiotic that inhibits bacterial cell wall synthesis.

  • Clavulanic Acid: Inhibits beta-lactamase enzymes that make some bacteria resistant to penicillins. This combination allows the medicine to target a wider range of bacteria.

Dosage

As prescribed by the physician depending on infection severity, patient age, and weight.
(Amoxicillin + Clavulanic Acid)

Side Effects

Possible side effects include:

  • Digestive issues: Nausea, vomiting, indigestion, diarrhea

  • Hypersensitivity: Rash, angioedema, anaphylaxis, serum sickness-like syndrome, hypersensitivity vasculitis

  • Hematological: Reversible leukopenia, neutropenia, thrombocytopenia

  • Other: Mucocutaneous candidiasis, dizziness, headache

Drug Interactions

  • Mycophenolate mofetil (reduced efficacy)

  • Probenecid (increases amoxicillin levels)

  • Oral contraceptives (may reduce efficacy)

  • Anticoagulants: acenocoumarol, warfarin (increased bleeding risk)

Indications

  • Effective against a broad spectrum of bacterial infections, including resistant strains due to clavulanic acid protection.

Contraindications / When Not to Use

❌ Do not use in:

  • Known hypersensitivity to beta-lactam antibiotics (e.g., penicillins, cephalosporins)

Precautions

  • Always evaluate patient history of allergies to penicillins or cephalosporins.

  • Monitor liver and kidney function in long-term use.

  • Adjust dose in renal impairment patients.

Warnings

  1. Hypersensitivity reactions (e.g., anaphylaxis, SCARs) can be severe or fatal—higher risk in those with penicillin allergy.

  2. Prolonged use can lead to overgrowth of non-susceptible organisms (superinfections).

  3. Dose adjustments are necessary in renal impairment to avoid toxicity.

Pregnancy Category

⚠️ Consult your doctor before use. It is generally considered safe but must be used under medical supervision during pregnancy.

Storage

✅ Store at room temperature, away from light and heat.