Actrapid Hm Injection 10ml

💉 Actrapid HM – Human Insulin Specification

📦 Requires Prescription:

Yes

💊 Generic Name:

Human Insulin

✅ Indicated For:

• Type 1 Diabetes Mellitus

• Type 2 Diabetes Mellitus (alone or with oral agents)

• Gestational Diabetes

• Emergency treatment of Diabetic Ketoacidosis

⚙️ How It Works:

Insulin binds to specific receptors on insulin-sensitive tissues (liver, muscles, adipose), resulting in:

• Inhibition of hepatic glucose production

• Increased peripheral glucose uptake

• Decreased lipolysis, preventing ketone formation
  ➤ Result: Lowered blood glucose concentration

🛡️ Usage & Safety

💊 Dosage:

• Human Insulin — As per doctor's prescription

🚫 When Not to Use:

• Hypersensitivity to components

• Hypoglycemia

• Hyperglycemic coma

⚠️ Side Effects

🩸 Common:

• Hypoglycemia:

  • Cold sweat, pale skin, tremors, confusion, fatigue, nausea, headache, palpitations

  • Severe cases: unconsciousness, brain damage, or death

• Weight Gain

• Oedema

• Vision changes (refraction anomalies)

🔴 Local Reactions:

• Redness, swelling, itching at injection site

• Lipodystrophy (fat loss or accumulation at site)

🌡️ Other Possible Reactions:

• General rash, itching, sweating

• GI upset

• Angioedema, breathing difficulty, palpitations

• Drop in blood pressure

🔄 Drug Interactions

• Increased insulin effect:

  • Beta blockers, MAOIs, ACE inhibitors, salicylates, alcohol

• Decreased insulin effect:

  • Oral contraceptives, thiazides, glucocorticoids, thyroid hormones, danazol, sympathomimetics

⚠️ Precautions & Warnings

🏃 Precaution:

• Care during exercise; may cause hypoglycemia

• Dose may need adjustment with:

  • Diet changes

  • Activity level changes

🛑 Warnings:

1. Insulin needs may increase during illness or emotional stress

2. Requires regular glucose and ketone monitoring

3. Hypersensitivity reactions (urticaria, angioedema, anaphylaxis)

   • May require desensitization therapy in rare cases

👶 Pregnancy Category:

• Use only after physician consultation

🧊 Storage Instructions:

• YES – Store in refrigerator (2°C–8°C)

• Do not freeze

• Keep away from light and children