Zipix 100 mg is a brand of Clozapine, an atypical antipsychotic medication primarily used to treat schizophrenia in patients who have not responded to other treatments. It is also utilized to reduce the risk of suicidal behavior in individuals with schizophrenia or similar disorders.

🩺 Primary Uses

• Treatment-Resistant Schizophrenia: Clozapine is effective for patients who have not responded adequately to standard antipsychotic therapies.

• Reduction of Suicidal Behavior: It helps decrease the risk of recurrent suicidal behavior in individuals with schizophrenia or schizoaffective disorder.

⚠️ Important Safety Information

Clozapine carries several significant risks and requires careful monitoring:

• Agranulocytosis: A potentially life-threatening decrease in white blood cells; regular blood tests are mandatory to monitor this risk.

• Seizures: The risk increases with higher doses; dose adjustments should be made cautiously.

• Myocarditis and Cardiomyopathy: Inflammation of the heart muscle; patients should be monitored for signs of heart issues.

• Orthostatic Hypotension: A sudden drop in blood pressure upon standing; dose titration should be gradual to mitigate this risk.

• Metabolic Changes: Including weight gain, hyperglycemia, and dyslipidemia; regular monitoring of metabolic parameters is recommended.

• Gastrointestinal Hypomotility: Severe constipation can occur; patients should be monitored for bowel function.

💊 Dosage & Administration

• Initiation: Typically starts at 12.5 mg once or twice daily, with gradual increases.

• Maintenance: The effective dose varies; however, doses above 900 mg/day are not recommended.

• Administration: Can be taken with or without food; consistency in timing helps maintain stable blood levels.