Cyclogest (Progesterone) 400mg is a prescription medication that contains micronised progesterone, a natural female hormone involved in the menstrual cycle and pregnancy. It is usually used in the form of vaginal or rectal pessaries (suppositories).

🩺 What Is It Used For?

Cyclogest 400mg is commonly prescribed for:

• Supporting pregnancy in women undergoing IVF or other fertility treatments

• Luteal phase support during Assisted Reproductive Technology (ART)

• Preventing preterm birth in women at risk

• Treating hormonal imbalances, including:

  • Irregular menstrual cycles

  • Premenstrual syndrome (PMS)

  • Postnatal depression

• Hormone Replacement Therapy (HRT) – to counteract estrogen's effects on the uterine lining in postmenopausal women

💊 How It’s Used

• Dose: Usually 400mg once or twice daily, as prescribed

• Route: Can be inserted vaginally or rectally

• Timing: Often at bedtime to reduce leakage (especially when used vaginally)

⚠️ Possible Side Effects

• Headache

• Nausea or abdominal discomfort

• Bloating

• Fatigue

• Breast tenderness

• Mood changes

• Vaginal irritation or discharge (if used vaginally)

If you experience severe side effects like chest pain, breathlessness, or allergic reactions, seek medical attention immediately.

🚫 Who Should Avoid It?

Avoid or use with caution if you have:

• A history of blood clots or stroke

• Liver disease

• Breast or genital cancers (unless your doctor specifically prescribes it)