Atcovate Lotion Specification

• Yes

Generics

• Fluticasone Propionate

Used For

• Eczema

How It Works

Fluticasone propionate is a corticosteroid that helps reduce inflammation. Corticosteroids are believed to act by inducing phospholipase A2 inhibitory proteins, collectively called lipocortins. These proteins inhibit the release of arachidonic acid, a precursor to inflammatory mediators like prostaglandins and leukotrienes.

Fluticasone propionate is lipophilic and binds strongly to glucocorticoid receptors, with a half-life of approximately 10 hours. It has minimal activity at other receptors such as progesterone, mineralocorticoid, estrogen, or androgen receptors.

Atcovate Lotion Usage and Safety

• Fluticasone Propionate (apply as directed by your physician).

Side Effects

• Irritation or itching.

• Burning sensation at the application site.

• Pustular psoriasis (raised bumps with pus under the skin).
• Worsening of the treated condition.
• Redness or rash.
• Hives.
• Stretch marks.
• Increased visibility of blood vessels under the skin.
• Skin color changes.
• Increased body hair.
• Skin thinning or wrinkling.
• Dryness.
• Weight gain and rounding of the face (Cushingoid appearance).
• Obesity.

Drug Interactions

Inform your doctor if you are taking:

• Ritonavir.
• Itraconazole.
• Any other medication that may interact with corticosteroids.

Indications

This lotion is indicated for the treatment of inflamed skin conditions such as dermatitis and eczema.

When Not to Use

• Contraindicated in patients with hypersensitivity to any of its components.

Atcovate Lotion Precautions

• Contains imidurea, which releases formaldehyde. This may cause allergic sensitization or irritation upon skin contact.
• Avoid use if hypersensitive to formaldehyde, as it may worsen dermatitis or delay healing.

Atcovate Lotion Warnings

1. Preexisting Conditions: Avoid use on areas with preexisting skin atrophy or active infection. Not suitable for rosacea or perioral dermatitis.
2. Appropriate Use: Use only for the condition for which it is prescribed.
3. Application Guidelines: Do not bandage, cover, or wrap the treated area unless directed by a physician.

Additional Information

• Always consult your physician before using any medication during pregnancy.

• Store at room temperature, away from direct light and heat.